MT-RNR1 Genotype Should Not Affect Childhood Vaccination-Unintended Consequences of Guidelines

John H McDermott; Joshua Wolf; William G Newman

doi:10.1001/jamapediatrics.2023.3263

MT-RNR1 Genotype Should Not Affect Childhood Vaccination-Unintended Consequences of Guidelines

JAMA Pediatr. 2023 Nov 1;177(11):1119-1120. doi: 10.1001/jamapediatrics.2023.3263.

Authors

John H McDermott^{1

2}, Joshua Wolf³, William G Newman^{1

2}

Affiliations

¹ Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
² Division of Evolution, Infection and Genomic Sciences, School of Biological Sciences, University of Manchester, Manchester, United Kingdom.
³ Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee.

PMID: 37695579
DOI: 10.1001/jamapediatrics.2023.3263

No abstract available

Plain language summary

This Viewpoint discusses whether routine vaccination is safe for children with MT-RNR1 gene variants that predispose to aminoglycoside-induced hearing loss.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Genetic Testing*
Genotype
Humans
Mutation
Vaccination*