Case of human rabies despite post-exposure prophylaxis (PEP) and complete recovery after intrathecal rabies immunoglobulin (RIG)

BMJ Case Rep. 2023 Sep 4;16(9):e256408. doi: 10.1136/bcr-2023-256408.

Abstract

Rabies, a fatal viral zoonotic disease, has become a public health concern in Sarawak, Malaysia. Despite pre-exposure and post-exposure prophylaxis being available, there has been limited progress in developing treatments for rabies, emphasising the pressing need for productive solutions. We present a laboratory-confirmed human rabies case in which the patient survived without neurological sequelae after receiving intrathecal rabies immunoglobulin.

Keywords: Infection (neurology); Tropical medicine (infectious disease).

Publication types

  • Case Reports
  • Retracted Publication

MeSH terms

  • Disease Progression
  • Humans
  • Immunoglobulins / therapeutic use
  • Immunologic Factors
  • Post-Exposure Prophylaxis*
  • Rabies* / drug therapy
  • Rabies* / prevention & control

Substances

  • Immunoglobulins
  • Immunologic Factors