Duration of monitoring after cessation of oxygen therapy in infants with bronchiolitis

J Paediatr Child Health. 2023 Nov;59(11):1223-1229. doi: 10.1111/jpc.16485. Epub 2023 Aug 31.

Abstract

Aim: There is no evidence for how long bronchiolitis patients should be observed after coming off oxygen therapy and wide practice variation exists. We aimed to investigate whether it is safe to discharge bronchiolitis patients 4 h after cessation of oxygen therapy.

Methods: A retrospective single-centre cohort study of 884 infants (n = 462 in 2018 vs. n = 422 in 2019) aged 0-24 months admitted with bronchiolitis in 2018 and 2019 was conducted after implementation of a bronchiolitis protocol recommending discharge home 4 h post-cessation of oxygen therapy in 2019. We compared the rate of readmissions and Clinical Reviews/Rapid Responses in the pre- and post-exposure cohorts.

Results: There was a significant reduction in median (interquartile range (IQR)) time to discharge post oxygen cessation by 87 min (510 (370-1033) min versus 423 (273-904) min; P < 0.001) and in median (IQR) length of stay by 6.7 h (2.11 (1.54-2.97) days vs. 1.83 (1.17-2.71) days; P < 0.001). There was no significant difference between readmissions in 2018 compared to 2019 (0.6% vs. 1.4%; P = 0.317). In 2018, there were two Clinical Reviews and in 2019 there were two Rapid Responses post-cessation of oxygen. There were 89 patients discharged within 4 h of cessation of oxygen therapy (n = 18 in 2018 vs. n = 71 in 2019; P < 0.001) with no readmissions, Clinical Reviews or Rapid Responses in the 2019 cohort.

Conclusions: This study demonstrates that patients can be discharged 4 h after cessation of supplemental oxygen without increased risk of adverse events.

Keywords: bronchiolitis; discharge criteria; duration of monitoring; length of stay; oxygen therapy.

MeSH terms

  • Bronchiolitis* / therapy
  • Cohort Studies
  • Humans
  • Infant
  • Length of Stay
  • Oxygen
  • Oxygen Inhalation Therapy / methods
  • Retrospective Studies

Substances

  • Oxygen