Decongestion strategies in patients presenting with acutely decompensated heart failure: A worldwide survey among physicians

Eur J Heart Fail. 2023 Sep;25(9):1555-1570. doi: 10.1002/ejhf.2985. Epub 2023 Sep 7.

Abstract

Aims: Decongestion strategies for acute decompensated heart failure (ADHF) characterized by volume overload differ widely. The aim of this independent international academic web-based survey was to capture the therapeutic strategies that physicians use to treat ADHF and to assess differences in therapeutic approaches between cardiologists versus non-cardiologists.

Methods and results: Physicians were invited to complete a web-based questionnaire, capturing anonymized data on physicians' characteristics and treatment preferences based on a hypothetical clinical scenario of a patient hospitalized with ADHF. A total of 641 physicians from 60 countries participated. A wide variation in the management of the patient was observed. There was conservative use of diuretics, i.e. only 7% started intravenous furosemide at a dose ≥2 times the baseline oral dose, and infrequent use of ultrasound in assessing congestion (20.4%). Spot urinary sodium was infrequently or never measured by ≥85% of physicians. A third considered a patient with ongoing oedema as being stabilized. There were significant differences between cardiologists and non-cardiologists in the management of ADHF, the targets for daily body weight loss and urine output, diuretic escalation strategies (66.3% vs. 40.7% would escalate diuresis by adding a thiazide) and assessment of response to treatment (27.0% vs. 52.9% considered patients with minimal congestion as stabilized).

Conclusions: There is substantial variability amongst physicians and between cardiologists and non-cardiologists in the management of patients with ADHF, with regard to clinical parameters used to tailor treatment, treatment goals, diuretic dosing and escalation strategies.

Keywords: Acute heart failure; Diuretics.

MeSH terms

  • Acute Disease
  • Diuretics / therapeutic use
  • Furosemide / therapeutic use
  • Heart Failure* / drug therapy
  • Humans
  • Physicians*
  • Surveys and Questionnaires
  • Treatment Outcome

Substances

  • Furosemide
  • Diuretics