Abstract
Hb Siriraj is a beta chain variant in which beta 7 (A4) Glu is replaced by a lysine. It has been encountered in association with Hb S in a black man from Martinique. Some properties of Hb Siriraj are compared, particularly, with Hb C [alpha 2 beta 26(A3)Glu----Lys], and a study of its in vitro interaction with Hb S is discussed.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Anemia, Sickle Cell / blood*
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Genetic Carrier Screening
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Genetic Variation
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Hemoglobin A / metabolism
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Hemoglobin, Sickle / metabolism*
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Hemoglobins, Abnormal / genetics
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Hemoglobins, Abnormal / metabolism*
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Hemolysis
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Humans
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Kinetics
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Male
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Middle Aged
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Syndrome
Substances
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Hemoglobin, Sickle
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Hemoglobins, Abnormal
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Hemoglobin A
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hemoglobin Siriraj