Research progress on the correlation between platelet aggregation and tumor progression

Histol Histopathol. 2024 Feb;39(2):145-152. doi: 10.14670/HH-18-646. Epub 2023 Jun 23.

Abstract

Platelets are generally considered as the main functional unit of the coagulation system. However, more and more studies have confirmed that platelets also have an important relationship with tumor progression. Tumor cells can utilize platelets to promote their own infiltration and hematogenous metastasis, and platelets are activated and aggregated in this process. Therefore, platelet aggregation may be a concomitant marker of tumor progression. This is of great significance for predicting tumor metastasis before timely treatments.

Publication types

  • Review

MeSH terms

  • Blood Platelets*
  • Humans
  • Neoplasm Metastasis / pathology
  • Platelet Aggregation*