Description of pathogenic bacteria in patients with respiratory symptoms associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Colombia

Ann Clin Microbiol Antimicrob. 2023 Jul 7;22(1):56. doi: 10.1186/s12941-023-00595-x.

Abstract

Viral respiratory infections may predispose to co-infections with other pathogenic microorganisms. In this study, pathogenic respiratory bacteria were detected using commercial kit Allplex Respiratory Panel 4 from nasopharyngeal samples from individuals suffering respiratory symptoms with and without severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients without respiratory symptoms were included as controls. Haemophilus influenzae and Streptococcus pneumoniae were detected from 12 patients (6%) in both, patients with respiratory symptoms (including hospitalized) (n = 6) and individual without symptoms (n = 6). Pathogenic bacteria possibly proliferate due to the limited immune response of patients with SARS-CoV-2, perhaps due to dysbiosis generated by the viral infection.

Keywords: Bacterial respiratory pathogens; Co-infection; Respiratory symptoms; SARS-CoV-2.

MeSH terms

  • COVID-19*
  • Colombia / epidemiology
  • Humans
  • Pneumonia*
  • SARS-CoV-2
  • Streptococcus pneumoniae