A case of complete resection of prostate stromal sarcoma after neoadjuvant chemotherapy

Abstract

Introduction: Prostatic stromal sarcoma is an extremely rare malignancy of the prostate with a poor prognosis.

Case presentation: A 65-year-old man presented with dyschezia, and computed tomography showed a large prostate mass. The diagnosis was prostate stromal sarcoma by transrectal needle biopsy. Magnetic resonance imaging suggested rectal infiltration. The patient underwent 4 courses of neoadjuvant chemotherapy with gemcitabine and docetaxel hydrate followed by total pelvic exenteration.

Conclusion: No recurrence has occurred at 5 years after the surgery. This is the first report of complete resection in prostate stromal sarcoma after neoadjuvant chemotherapy with gemcitabine and docetaxel hydrate.

Keywords: docetaxel; gemcitabine; neoadjuvant chemotherapy; prostate; stromal sarcoma.