Eosinophil-independent IL-5 levels are increased in critically ill COVID-19 patients who survive

Allergy Asthma Clin Immunol. 2023 Jul 4;19(1):58. doi: 10.1186/s13223-023-00810-6.

Xiaotian Ju^#¹, Kiho Son^#¹, Rameen Jamil², Sarah Culgin², Brittany Salter¹, Kate Miyasaki¹, Nahal Emami Fard¹, Maria Xiao¹, Zil Patel¹, Kayla Zhang^{1

2}, Braeden Cowbrough^{1

3}, Melanie Kjarsgaard^{1

2}, Katherine Radford^{1

2}, Anna Dvorkin-Gheva³, Carl D Richards^{1

3}, Gerard Cox^{1

2}, Zain Chagla^{1

2}, Marek Smieja¹, Marcel Tunks¹, Waleed Alhazzani¹, Dawn M E Bowdish^{1

2

3}, Dan Perri^{1

2}, Parameswaran K Nair^{1

2}, Roma Sehmi^{4

5}, Manali Mukherjee^{6

7

8}

¹ Department of Medicine, McMaster University, Hamilton, ON, Canada.
² Firestone Institute for Respiratory Health, Research Institute of St. Joe's, Hamilton, ON, Canada.
³ McMaster Immunology Research Centre, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
⁴ Department of Medicine, McMaster University, Hamilton, ON, Canada. sehmir@mcmaster.ca.
⁵ Firestone Institute for Respiratory Health, Research Institute of St. Joe's, Hamilton, ON, Canada. sehmir@mcmaster.ca.
⁶ Department of Medicine, McMaster University, Hamilton, ON, Canada. mukherj@mcmaster.ca.
⁷ Firestone Institute for Respiratory Health, Research Institute of St. Joe's, Hamilton, ON, Canada. mukherj@mcmaster.ca.
⁸ McMaster Immunology Research Centre, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada. mukherj@mcmaster.ca.

^# Contributed equally.

No abstract available

Keywords: CD4; CD8; COVID-19; Eosinophils; GATA-3; IL-13; IL-5; T cells; T2 cytokines.

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