Ovarian reserve after treatment of ovarian endometriomas by ethanolic sclerotherapy compared to surgical treatment

Eur Rev Med Pharmacol Sci. 2023 Jun;27(12):5575-5582. doi: 10.26355/eurrev_202306_32795.

Abstract

Objective: To preserve ovarian reserve, we treated ovarian endometriomas by ultrasound-guided aspiration followed by sclerotherapy of the cyst mucosa. We compared the results with laparoscopic cystectomy.

Patients and methods: We conducted a retrospective study of 96 women with ovarian endometriomas. In 54 of the women, ultrasound-guided aspiration of the contents was performed, followed by chemical sclerotherapy of the cyst plaque with ethanol. Laparoscopic cystectomy was performed in the remaining 42 women.

Results: Statistical analysis of anti-Mullerian hormone (AMH) levels before and after the procedures showed a significant decrease in the case of cystectomy compared with ethanolic ovarian sclerotherapy (EOS).

Conclusions: Conservative treatment by echo-assisted puncture and sclerotherapy with ethanol proved to be a viable treatment for the removal of ovarian endometriomas. It is a simple procedure that does not affect ovarian reserve or fertility.

MeSH terms

  • Cysts*
  • Endometriosis* / surgery
  • Ethanol / therapeutic use
  • Female
  • Humans
  • Laparoscopy* / methods
  • Ovarian Cysts* / surgery
  • Ovarian Reserve*
  • Retrospective Studies
  • Sclerotherapy

Substances

  • Ethanol