A randomized cross-over trial investigating the neurocognitive effects of acute exercise on face recognition in children with autism spectrum disorder

Autism Res. 2023 Aug;16(8):1630-1639. doi: 10.1002/aur.2977. Epub 2023 Jun 23.

Abstract

Difficulties in face recognition contribute to social-cognitive problems in autistic children. Evidence on behavioral interventions targeting this cognitive domain is limited. In non-autistic individuals, a single exercise session is known to elicit temporary benefits for several cognitive functions. Our study investigates whether acute aerobic exercise influences face recognition in autistic children. In a randomized order, 29 participants completed a 20-min moderately-intense cycling bout on an ergometer and a control condition. Before and after each condition, participants categorized Mooney faces and instruments during a computerized cognitive task. Simultaneously, the N170 component of event-related potentials and pupil size were recorded using electroencephalography and eyetracking, respectively. As indicated by a greater increase of reaction time in the exercise compared to the control condition, the results revealed impaired face recognition following aerobic exercise. This effect was accompanied by a lower decrease of the positive N170 amplitude and a trend towards a greater constriction of the pupil size in the exercise compared to the control condition. Our findings highlight the interplay of the physiological state and face recognition in autistic children. Exercise-induced impairments in this social-cognitive ability may be due to an interference with the learning effect that is typically seen for the structural encoding of faces.

Keywords: N170; event-related potentials; eye-tracking; pupil size; social cognition.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Autism Spectrum Disorder* / complications
  • Child
  • Cross-Over Studies
  • Electroencephalography / methods
  • Evoked Potentials / physiology
  • Exercise / physiology
  • Facial Recognition* / physiology
  • Humans