Vertigo and Dizziness After Coronavirus Disease-2019 Vaccination: A Nationwide Analysis

J Int Adv Otol. 2023 Jun;19(3):228-233. doi: 10.5152/iao.2023.22937.

Abstract

Background: Side effects occurring after COVID-19 vaccination can include vertigo and dizziness. Despite its high incidence, few studies to date have assessed dizziness/vertigo after vaccination. The present study investigated the incidence of dizziness/vertigo after COVID-19 vaccination in South Korea.

Methods: Adverse reactions to COVID-19 vaccination reported to the Korea Disease Control and Prevention Agency from February 26, 2021, to July 31, 2022 (week 74) were analyzed. The incidence rates of dizziness/vertigo in subjects vaccinated with 5 COVID-19 vaccines, AZD1222 (AstraZeneca), BNT162b2 (Pfizer-BioNTech), JNJ-78436735 (Janssen), mRNA-1273 (Moderna), and NVX-CoV2373 (Novavax), were determined.

Results: A total of 126 725 952 doses of COVID-19 vaccine were administered, with 473 755 suspected adverse reactions (374 per 100 000 vaccinations) reported. Vertigo/dizziness was reported after the administration of 68 759 doses, or 54.3 per 100 000 vaccinations, making it the third most common adverse reaction after headache and muscle pain.

Conclusion: Dizziness/vertigo was generally a mild adverse reaction after COVID-19 vaccination, but it was the third most common adverse reaction in Korea. Studies are necessary to clarify the causal relationship between vaccination and dizziness/vertigo and to prepare subjects for this possible adverse reaction.

MeSH terms

  • Ad26COVS1
  • BNT162 Vaccine
  • COVID-19 Vaccines / adverse effects
  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • ChAdOx1 nCoV-19
  • Coronavirus*
  • Dizziness / chemically induced
  • Dizziness / epidemiology
  • Humans
  • Vaccination / adverse effects
  • Vertigo / chemically induced
  • Vertigo / epidemiology

Substances

  • COVID-19 Vaccines
  • Ad26COVS1
  • BNT162 Vaccine
  • ChAdOx1 nCoV-19