Unusual presentation of adult granulosa cell tumor. A case report and review of the literature

Int Cancer Conf J. 2023 Mar 30;12(3):190-194. doi: 10.1007/s13691-023-00603-z. eCollection 2023 Jul.

Abstract

Extraovarian adult granulosa cell tumor is a very uncommon neoplasm, which probably arises from the ectopic gonadal tissue along the embryonic root of the genital ridge. We report a new and rare case of an extraovarian adult granulosa cell tumor occurring in a 66-year-old woman who was presented with severe abdominal pain focused on the left iliac fossa. The immunohistopathology confirmed the diagnosis of a paratubal adult granulosa cell tumor. This paper illustrates the histogenetic origin of granulosa cell tumor, its clinicopathological and immunohistochemical features.

Keywords: Adult granulosa cell tumor; Differential diagnosis; Extraovarian; Histopathology; Inhibin.