A 24-Year-Old Woman With Cough, Arthralgia, and Skin Ulcerations

Thibault Leveque; Anastasia Pavlidi; Thomas Lacoste-Palasset; Aurélie Cazes; Jonathan Messika; Philippe Montravers; Brice Lortat-Jacob; Yves-Hervé Castier; Vincent Bunel; Raphaël Borie; Damien Sène; Yves Allenbach; Bruno Mégarbane; Cloé Comarmond

doi:10.1016/j.chest.2022.12.038

A 24-Year-Old Woman With Cough, Arthralgia, and Skin Ulcerations

Chest. 2023 May;163(5):e223-e229. doi: 10.1016/j.chest.2022.12.038.

Affiliations

¹ Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Université Paris Cité, Paris, France.
² Department of Internal Medicine and Clinical Immunology, Lariboisière Hospital, Université Paris Cité, Paris, France.
³ Department of Pathology, Lariboisière Hospital, Université Paris Cité, Paris, France.
⁴ Pulmonology B and Lung Transplantation Department, Bichat Claude Bernard Hospital, Université Paris Cité, Paris, France.
⁵ Department of Anaesthesiology and Critical Care Medicine, Bichat Claude Bernard Hospital, Université Paris Cité, Paris, France.
⁶ Thoracic Surgery Department, Bichat Claude Bernard Hospital, Université Paris Cité, Paris, France.
⁷ Pulmonology A Department, Bichat Claude Bernard Hospital, Université Paris Cité, Paris, France.
⁸ Department of Internal Medicine and Clinical Immunology, Pitié-Salpêtrière Hospital, Sorbonne Université, Paris, France.
⁹ Department of Internal Medicine and Clinical Immunology, Lariboisière Hospital, Université Paris Cité, Paris, France. Electronic address: chloe.comarmondortoli@aphp.fr.

PMID: 37164587
DOI: 10.1016/j.chest.2022.12.038

Abstract

A 24-year-old Senegalese woman without remarkable history except anemia and iron deficiency related to excessive menstrual bleeding and sickle cell trait was admitted to our internal medicine department with 4-month fever, weight loss (-13 kg), dyspnea for limited efforts, intermittent productive cough, and bilateral metacarpophalangeal (MCP) and interphalangeal arthralgia. She was born and lived in France. She traveled previously to Senegal in 2015. She had no history of tobacco, alcohol, or drug use nor proximity with animals. She was taking no medication.

Keywords: ECMO; anti-MDA5; interstitial lung disease; lung transplantation.

Publication types

Case Reports

MeSH terms

Arthralgia / diagnosis
Arthralgia / etiology
Cough* / diagnosis
Cough* / etiology
Diagnosis, Differential
Dyspnea*
Female
France
Humans