Diffuse gastric polyposis in a young patient with a giant retroperitoneal mass: A case report

Guangbing Duan; Huihui Sun; Ye Chen; Junwen Wang; Yu Zeng; Shurong Ji; Jie Xiong; Ying Chen; Wenfang Liu; Shuchang Xu

doi:10.3892/etm.2023.11925

Diffuse gastric polyposis in a young patient with a giant retroperitoneal mass: A case report

Exp Ther Med. 2023 Mar 30;25(5):226. doi: 10.3892/etm.2023.11925. eCollection 2023 May.

Authors

Guangbing Duan¹, Huihui Sun¹, Ye Chen¹, Junwen Wang¹, Yu Zeng², Shurong Ji³, Jie Xiong¹, Ying Chen¹, Wenfang Liu³, Shuchang Xu¹

Affiliations

¹ Department of Gastroenterology, Tongji Institute of Digestive Disease, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, P.R. China.
² Department of Pathology, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, P.R. China.
³ Department of General Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, P.R. China.

Abstract

Familial adenomatous polyposis (FAP) is characterized by hundreds of colonic adenomatous polyps and extraintestinal manifestations beginning in adolescence and early adulthood. It is also one of the most common hereditary colorectal cancer syndromes. In this case study, a rare phenotype of FAP associated with diffuse gastric polyposis, colon oligo-polyposis, and a massive retroperitoneal mass is described. The results expand on the current body of knowledge of FAP and may represent a new phenotypic expression of FAP. Accurate evidence-based surveillance and management recommendations for this disease require further research and evaluation.

Keywords: case report; colonic adenomatous polyps; familial adenomatous polyposis; gastric polyposis; retroperitoneal mass.

Publication types

Case Reports

Grants and funding

Funding: This work was supported by the National Natural Science Foundation of China (grant no. 81974067), Science and Technology Innovation Plan of Shanghai Science and Technology Commission (grant no. 21Y11908500), Shanghai Informatization Development Special project (grant no. 202001003), and the Psychosomatic Medicine Project of Key Developing Disciplines of Shanghai Municipal Health Commission (grant no. 2019ZB0202).