Associations between short-term exposure to ambient PM2.5 and incident cases of cardiovascular disease in Yantai, China

Int J Environ Health Res. 2024 Feb;34(2):1124-1135. doi: 10.1080/09603123.2023.2202899. Epub 2023 Apr 24.

Abstract

There are limited studies investigating the association between short-term exposure to PM2.5 and incident cardiovascular disease (CVD) cases in China. This study aims to examine the short-term effects of PM2.5 on the incidence of cardiovascular diseases. A combination of Poisson-distribution generalized linear model and distributed lag non-linear model was used to examine the association between short-term exposure to PM2.5 and incident cases of CVD. The results revealed that per 10 µg/m3 increment of PM2.5 would increase the incident CVD cases by 0.147% (Relative Risk: 1.00147, 95% Confidence Interval: 1.00008-1.00286) at a lag of 2 days. The stratified analyses showed higher effects risk in females, older residents (aged 60-75 years), and acute myocardial infarction group (p-value for difference <0.05). This study indicates that short-term exposure to PM2.5 may increase the risk of CVD and highlights the necessity for a higher air quality standard in Yantai, China.

Keywords: Air pollution; PM2.5; cardiovascular disease; generalized linear model; incident cases.

MeSH terms

  • Air Pollutants* / analysis
  • Air Pollutants* / toxicity
  • Air Pollution* / adverse effects
  • Air Pollution* / analysis
  • Cardiovascular Diseases* / chemically induced
  • Cardiovascular Diseases* / epidemiology
  • China / epidemiology
  • Environmental Exposure / analysis
  • Female
  • Humans
  • Particulate Matter / analysis
  • Particulate Matter / toxicity

Substances

  • Air Pollutants
  • Particulate Matter