Tryptanthrin-malononitrile adduct for highly efficient turn-off fluorescent sensing of aniline

Haitham K R Al-Sharifi; Arsha Rajan; S L Sruthi; Ani Deepthi

doi:10.1016/j.saa.2023.122755

Tryptanthrin-malononitrile adduct for highly efficient turn-off fluorescent sensing of aniline

Spectrochim Acta A Mol Biomol Spectrosc. 2023 Sep 5:297:122755. doi: 10.1016/j.saa.2023.122755. Epub 2023 Apr 18.

Authors

Haitham K R Al-Sharifi¹, Arsha Rajan¹, S L Sruthi¹, Ani Deepthi²

Affiliations

¹ Department of Chemistry, University of Kerala, Kariavattom, Trivandrum 695581, India.
² Department of Chemistry, University of Kerala, Kariavattom, Trivandrum 695581, India. Electronic address: anideepthi@gmail.com.

PMID: 37087813
DOI: 10.1016/j.saa.2023.122755

Abstract

The fluorescence quenching of 2-(8-chloro-12-oxo-12H-indolo[2,1-b]quinazolin-6-ylidene)-malononitrile (5a) by aniline was studied in detail. Time correlated single photon counting measurements (TCSPC) indicated that the quenching involved both static and dynamic mechanisms without ground state complex formation. The selectivity towards aniline sensing in presence of other amines/aromatics and the anti-interference studies together with the low LOD value indicates the potential of 5a as a molecular probe for aniline sensing which is unaffected by pH alteration as well.

Keywords: Detection; Dynamic; Quenching; Static; Tryptanthrin.