1 From the Department of Anesthesia and Intensive Care, AOU Policlinico San Marco, Catania, Italy (MS), the Department of Anesthesia and Intensive Care, Regional University Hospital of Montpellier, St-Eloi Hospital, University of Montpellier, Phymedexp, Université de Montpellier, Inserm, CNRS, CHRU de Montpellier, Montpellier, France (AdJ), the Division of Anaesthesia, Analgesia, and Intensive Care, University Hospital of Perugia, Italy (EdR), the Department of Anaesthesiology and Pain Medicine, Bern University Hospital, University of Bern, Bern, Switzerland (RG), the School of Medicine, Sigmund Freud University Vienna, Vienna, Austria (RG).