A Case of Fulminant Right Heart Failure Owing to Tumoral Pulmonary Hypertension

Kedong Wang; Anuj Verma; Kaitlin E Fish; Jiun-Ruey Hu; P Elliott Miller; Jon S Morrow; Inderjit Singh; Lawrence H Young

doi:10.1016/j.jaccas.2022.101715

A Case of Fulminant Right Heart Failure Owing to Tumoral Pulmonary Hypertension

JACC Case Rep. 2023 Mar 15:10:101715. doi: 10.1016/j.jaccas.2022.101715.

Authors

Kedong Wang¹, Anuj Verma², Kaitlin E Fish², Jiun-Ruey Hu¹, P Elliott Miller¹, Jon S Morrow², Inderjit Singh³, Lawrence H Young¹

Affiliations

¹ Department of Internal Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
² Department of Pathology, Yale School of Medicine, New Haven, Connecticut, USA.
³ Department of Internal Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

Abstract

Tumoral pulmonary hypertension is a rare cause of pulmonary hypertension. We report a patient who was thought to have idiopathic pulmonary arterial hypertension, but later developed fulminant right heart failure ultimately leading to death. Autopsy revealed substantial pulmonary tumor embolism burden originating from liver adenocarcinoma. (Level of Difficulty: Advanced.).

Keywords: acute heart failure; cancer; pulmonary hypertension.