Endoscopy in Pediatric Eosinophilic Esophagitis

Ramy Sabe; Girish Hiremath; Kenneth Ng

doi:10.1016/j.giec.2022.10.003

Endoscopy in Pediatric Eosinophilic Esophagitis

Gastrointest Endosc Clin N Am. 2023 Apr;33(2):323-339. doi: 10.1016/j.giec.2022.10.003.

Authors

Ramy Sabe¹, Girish Hiremath², Kenneth Ng³

Affiliations

¹ Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Rainbow Babies and Children's Hospitals, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
² Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University Medical Center, 11226, 2200 Children's Way, Nashville, TN 37232, USA.
³ Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Johns Hopkins Children's Center, Johns Hopkins University School of Medicine, 600 North Wolfe Street, CMSC 2-116, Baltimore, MD 21287, USA. Electronic address: kng13@jhmi.edu.

PMID: 36948749
DOI: 10.1016/j.giec.2022.10.003

Abstract

Eosinophilic esophagitis (EoE) is a chronic allergen-mediated clinicopathologic condition that currently requires esophagogastroduodenoscopy with biopsies and histologic evaluation to diagnose and monitor its progress. This state-of-the art review outlines the pathophysiology of EoE, reviews the application of endoscopy as a diagnostic and therapeutic tool, and discusses potential complications related to therapeutic endoscopic interventions. It also introduces recent innovations that can enhance the endoscopist's ability to diagnose and monitor EoE with minimally invasive procedures and perform therapeutic maneuvers more safely and effectively.

Keywords: Dysphagia; Eosinophilic esophagitis; Esophageal dilation; Food allergy; Food impaction.

Publication types

Review

MeSH terms

Biopsy
Child
Endoscopy, Gastrointestinal
Enteritis
Eosinophilia
Eosinophilic Esophagitis* / therapy
Gastritis
Humans

Supplementary concepts

Eosinophilic enteropathy