Patient specific contouring region of interest for abdominal stereotactic adaptive radiotherapy

Alex T Price; Christopher J Zachary; Eric Laugeman; Borna Maraghechi; Tong Zhu; Lauren E Henke

doi:10.1016/j.phro.2023.100423

Patient specific contouring region of interest for abdominal stereotactic adaptive radiotherapy

Phys Imaging Radiat Oncol. 2023 Feb 3:25:100423. doi: 10.1016/j.phro.2023.100423. eCollection 2023 Jan.

Authors

Alex T Price¹, Christopher J Zachary¹, Eric Laugeman¹, Borna Maraghechi¹, Tong Zhu¹, Lauren E Henke¹

Affiliation

¹ Washington University in St. Louis School of Medicine, St. Louis, MO, 63108, USA.

Abstract

Contouring during adaptive radiotherapy (ART) can be a time-consuming process. This study describes the generation of patient specific contouring regions of interest (CRoI) for evaluating the high dose fall-off in stereotactic abdominal ART. An empirical equation was derived to determine the radius of a cylindrical patient specific CRoIs. These CRoIs were applied to 60 patients and their adaptive fractions (301 unique treatment plans). Out of the 301 unique treatment plans, 284 (94%) treatment plans contained the high dose fall-off within the CRoI. There was an expected predicted average timesaving of 2.9-min-per case. Patient specific CRoIs improves the efficiency of ART.

Keywords: Adaptive radiotherapy; CBCTgRT; Gastrointestinal SBRT; MRgRT; SBRT.