A wheat kinase and immune receptor form host-specificity barriers against the blast fungus

Sanu Arora; Andrew Steed; Rachel Goddard; Kumar Gaurav; Tom O'Hara; Adam Schoen; Nidhi Rawat; Ahmed F Elkot; Andrey V Korolev; Catherine Chinoy; Martha H Nicholson; Soichiro Asuke; Rea Antoniou-Kourounioti; Burkhard Steuernagel; Guotai Yu; Rajani Awal; Macarena Forner-Martínez; Luzie Wingen; Erin Baggs; Jonathan Clarke; Diane G O Saunders; Ksenia V Krasileva; Yukio Tosa; Jonathan D G Jones; Vijay K Tiwari; Brande B H Wulff; Paul Nicholson

doi:10.1038/s41477-023-01357-5

A wheat kinase and immune receptor form host-specificity barriers against the blast fungus

Nat Plants. 2023 Mar;9(3):385-392. doi: 10.1038/s41477-023-01357-5. Epub 2023 Feb 16.

Authors

Sanu Arora^#¹, Andrew Steed^#¹, Rachel Goddard^#^{1

2}, Kumar Gaurav^#^{1

3}, Tom O'Hara^#¹, Adam Schoen⁴, Nidhi Rawat⁴, Ahmed F Elkot⁵, Andrey V Korolev¹, Catherine Chinoy¹, Martha H Nicholson¹, Soichiro Asuke⁶, Rea Antoniou-Kourounioti^{1

7}, Burkhard Steuernagel¹, Guotai Yu^{1

8}, Rajani Awal¹, Macarena Forner-Martínez¹, Luzie Wingen¹, Erin Baggs⁹, Jonathan Clarke¹, Diane G O Saunders¹, Ksenia V Krasileva⁹, Yukio Tosa⁶, Jonathan D G Jones¹⁰, Vijay K Tiwari⁴, Brande B H Wulff^{11

12}, Paul Nicholson¹³

Affiliations

¹ John Innes Centre, Norwich Research Park, Norwich, UK.
² Limagrain UK Ltd, Lincolnshire, UK.
³ European Molecular Biology Laboratory, European Bioinformatics Institute EMBL-EBI, Hinxton, UK.
⁴ Department of Plant Science and Landscape Architecture, University of Maryland, College Park, MD, USA.
⁵ Wheat Research Department, Field Crops Research Institute, Agricultural Research Center, Giza, Egypt.
⁶ Graduate School of Agricultural Science, Kobe University, Kobe, Japan.
⁷ School of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
⁸ Center for Desert Agriculture, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
⁹ Department of Plant and Microbial Biology, University of California, Berkeley, CA, USA.
¹⁰ The Sainsbury Laboratory, Norwich Research Park, Norwich, UK.
¹¹ John Innes Centre, Norwich Research Park, Norwich, UK. brande.wulff@kaust.edu.sa.
¹² Center for Desert Agriculture, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia. brande.wulff@kaust.edu.sa.
¹³ John Innes Centre, Norwich Research Park, Norwich, UK. paul.nicholson@jic.ac.uk.

^# Contributed equally.

Abstract

Since emerging in Brazil in 1985, wheat blast has spread throughout South America and recently appeared in Bangladesh and Zambia. Here we show that two wheat resistance genes, Rwt3 and Rwt4, acting as host-specificity barriers against non-Triticum blast pathotypes encode a nucleotide-binding leucine-rich repeat immune receptor and a tandem kinase, respectively. Molecular isolation of these genes will enable study of the molecular interaction between pathogen effector and host resistance genes.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Research Support, Non-U.S. Gov't

MeSH terms

Bangladesh
Brazil
Magnaporthe*
Plant Diseases / genetics
Plant Diseases / microbiology
Triticum* / genetics
Triticum* / microbiology

Abstract

Publication types

MeSH terms

Grants and funding