An Outbreak of Coxsackievirus B Type 2 Acute Meningoencephalitis in Children, Israel, July-September 2022

Or Kriger; Alon Abramovich; Ilana S Fratty; Eyal Leshem; Sharon Amit; Michal Stein; Bruria Ben-Zeev; Sara Via-Dorembus; Chen Hoffmann; Shira Rabinowicz; Merav Weil

doi:10.1097/INF.0000000000003876

An Outbreak of Coxsackievirus B Type 2 Acute Meningoencephalitis in Children, Israel, July-September 2022

Pediatr Infect Dis J. 2023 May 1;42(5):e177-e179. doi: 10.1097/INF.0000000000003876. Epub 2023 Feb 14.

Authors

Or Kriger^{1

2}, Alon Abramovich¹, Ilana S Fratty¹, Eyal Leshem^{1

3}, Sharon Amit¹, Michal Stein^{1

2

3}, Bruria Ben-Zeev^{1

2

3}, Sara Via-Dorembus^{1

2}, Chen Hoffmann^{1

3}, Shira Rabinowicz^{1

2

3}, Merav Weil¹

Affiliations

¹ From the Chaim Sheba Medical Center, Tel Hashomer, Israel.
² Safra Children Hospital, Chaim Sheba Medical Center, Tel Hashomer, Israel.
³ Tel Aviv University Sackler School of Medicine, Ramat Aviv, Israel.

PMID: 36795579
DOI: 10.1097/INF.0000000000003876

Abstract

During July-September 2022, 14 children suffering from meningoencephalitis tested positive for Coxsackievirus B2 (8 cerebrospinal fluid, 9 stool samples). Mean age 22 months (range 0-60 months); 8 were males. Seven of the children presented with ataxia and 2 had imaging features of rhombencephalitis, not previously described in association with Coxsackievirus B2.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Child
Child, Preschool
Coxsackievirus Infections* / complications
Coxsackievirus Infections* / epidemiology
Disease Outbreaks
Enterovirus B, Human
Female
Humans
Infant
Infant, Newborn
Israel / epidemiology
Male
Meningoencephalitis* / epidemiology