Current territorial organization for access to revascularization therapies for acute ischemic stroke in the Veneto region (Italy) from 2017 to 2021

Neurol Sci. 2023 Jun;44(6):2033-2039. doi: 10.1007/s10072-023-06662-7. Epub 2023 Feb 8.

Abstract

Introduction: To evaluate the access to treatments with intravenous thrombolysis (IVT) and/or mechanical thrombectomy (MT) in acute ischemic stroke patients admitted to stroke units (SUs) of Veneto region (Italy) according to current "hub-and-spoke" model from 2017 to 2021.

Patients and methods: We retrospectively analyzed data on treatments with IVT and/or MT for stroke patients admitted to the 23 SUs (6 Hubs and 17 Spokes) of the 6 macro-areas including 9 local sanitary units (LSUs) and 2 hospitals.

Results: We reported 6093 treatments with IVT alone, 1114 with IVT plus MT, and 921 with MT alone. Number of stroke unit (SU) beds/100,000 inhabitants ranges from 2.3 to 2.8, and no difference was found among different macro-areas. Number of treatments/100,000 inhabitants/year ranges from 19 to 34 for IVT alone, from 2 to 7 for IVT plus MT, and from 2 to 5 for MT alone. Number of IVT alone/SU bed/year ranges from 9 to 21 in the Hub and from 6 to 12 in the Spokes. Rate of IVT plus MT in patients directly arrived in the same LSU's Hub ranges from 50 to 81%, likewise the one of MT alone ranges from 49 to 84%.

Conclusions: Treatment target rates of IVT and MT set by Action Plan for Stroke in Europe 2018-2030 has been globally exceeded in the Veneto region. However, the target rate of MT and access revascularization treatments is heterogeneous among different macro-areas. Further efforts should be made to homogenize the current territorial organization.

Keywords: Hub-and-spoke model; Stroke; Thrombectomy; Thrombolysis.

MeSH terms

  • Brain Ischemia* / epidemiology
  • Brain Ischemia* / surgery
  • Fibrinolytic Agents
  • Humans
  • Ischemic Stroke* / epidemiology
  • Ischemic Stroke* / surgery
  • Italy / epidemiology
  • Retrospective Studies
  • Stroke* / epidemiology
  • Stroke* / surgery
  • Thrombectomy
  • Thrombolytic Therapy
  • Treatment Outcome

Substances

  • Fibrinolytic Agents