Impact of small molecule-mediated inhibition of ammonia detoxification on lung malignancies and liver metabolism
Cancer Commun (Lond)
.
2023 Apr;43(4):508-512.
doi: 10.1002/cac2.12402.
Epub 2023 Jan 28.
Authors
Georgios Makris
1
2
,
Semih Kayhan
1
,
Marvin Kreuzer
3
,
Véronique Rüfenacht
1
,
Erica Faccin
3
,
Jarl Underhaug
4
5
,
Carmen Diez-Fernandez
1
6
,
Philip A Knobel
3
7
,
Martin Poms
8
,
Nadine Gougeard
9
,
Vicente Rubio
9
,
Aurora Martinez
4
,
Martin Pruschy
3
,
Johannes Häberle
1
Affiliations
1
Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
2
Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.
3
Department of Radiation Oncology, Laboratory for Applied Radiobiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
4
Department of Biomedicine, University of Bergen, Bergen, Norway.
5
Department of Chemistry, University of Bergen, Bergen, Norway.
6
NUVISAN GmbH, Neu-Ulm, Bavaria, Germany.
7
CDR Life Inc., Schlieren, Zurich, Switzerland.
8
Division of Clinical Chemistry and Biochemistry, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
9
Instituto de Biomedicina de Valencia (IBV-CSIC), CIBER de Enfermedades Raras (CIBERER-ISCIII), Valencia, Spain.
PMID:
36708276
PMCID:
PMC10091103
DOI:
10.1002/cac2.12402
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
MeSH terms
Ammonia* / metabolism
Humans
Liver
Lung Neoplasms* / metabolism
Substances
Ammonia