Sequence and expression of the chicken calcitonin gene

FEBS Lett. 1987 Oct 19;223(1):63-8. doi: 10.1016/0014-5793(87)80510-0.

Abstract

The avian calcitonin gene was isolated and sequenced; two mRNAs are expressed by tissue-specific alternate splicing. The peptides encoded by the mRNAs are the protein precursors of either calcitonin or calcitonin gene-related peptide (CGRP). Calcitonin is expressed predominantly in ultimobranchial bodies and CGRP in brain.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Brain / physiology
  • Calcitonin / genetics*
  • Chickens / genetics*
  • Gene Expression Regulation
  • Genes
  • Molecular Sequence Data
  • Sequence Homology, Nucleic Acid

Substances

  • Calcitonin

Associated data

  • GENBANK/X06311
  • GENBANK/X06312
  • GENBANK/X06313
  • GENBANK/X06314
  • GENBANK/X06315