Abstract
Significant differences in values of the volume of ethacizine distribution and clearance at oral administration in patients with myocardial infarction from those in patients with other pathology were established. A considerable decrease of ethacizine bioavailability in myocardial infarction patients was shown.
MeSH terms
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Administration, Oral
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Anti-Arrhythmia Agents / administration & dosage
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Anti-Arrhythmia Agents / pharmacokinetics*
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Arrhythmias, Cardiac / drug therapy
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Arrhythmias, Cardiac / metabolism*
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Biological Availability
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Humans
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Injections, Intravenous
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Mathematics
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Myocardial Infarction / drug therapy
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Myocardial Infarction / metabolism
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Phenothiazines / administration & dosage
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Phenothiazines / pharmacokinetics*
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Time Factors
Substances
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Anti-Arrhythmia Agents
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Phenothiazines
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ethacizine