Tight Glycemic Control, Inflammation, and the ICU: Evidence for Heterogeneous Treatment Effects in Two Randomized Controlled Trials

Affiliations

• ¹ Divisions of Critical Care Medicine and Allergy, Immunology, and Bone Marrow Transplant.
• ² Division of General Internal Medicine and Health Sciences Research, Department of Medicine, and.
• ³ Department of Cardiology and.
• ⁴ Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
• ⁵ Division of Critical Care Medicine, Department of Pediatrics.
• ⁶ Department of Neurology, and.
• ⁷ Division of Clinical and Translational Research, Department of Anesthesia, Washington University, Saint Louis, Missouri.
• ⁸ Departments of Medicine and Anesthesia, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California.
• ⁹ Division of Plastic Surgery, Department of Surgery, and.
• ¹⁰ Department of Immunology, University of Toronto, Toronto, Ontario, Canada; and.
• ¹¹ Division of Medical Critical Care, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.
• ¹² Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
• ¹³ Division of Critical Care Medicine, Department of Pediatrics, University of California, Los Angeles, Los Angeles, California.