An Unusual Presentation of HCC in a Patient with No Underlying Liver Disease: A Case Study

Case Rep Oncol. 2022 Nov 8;15(3):995-1000. doi: 10.1159/000526929. eCollection 2022 Sep-Dec.

Abstract

Pedunculated hepatocellular carcinoma (P-HCC) is a rare subtype of HCC. P-HCC may occur in patients without underlying liver cirrhosis and can be present with negative serum tumor markers. With a growing worldwide incidence of nonalcoholic fatty liver disease, non-cirrhotic HCC will likely become more prevalent. We report a patient presenting to the hospital with nonspecific symptoms of weight loss, abdominal discomfort, and early satiety. Abdomen palpation found a large firm mass in the right middle abdomen. Computed tomography imaging showed a large right abdominal mass without evidence of liver attachment. The patient underwent a diagnostic laparotomy where a single 17 cm exophytic mass originating from the left liver lobe was found and resected. Clear margins were attained, and pathology demonstrated HCC. Early diagnosis of HCC is critical to achieving curative treatment, and physicians should keep P-HCC in mind when presented with a similar patient.

Keywords: Hepatocellular carcinoma; Pedunculated hepatocellular carcinoma; Surgical oncology.

Publication types

  • Case Reports

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No funding was provided in the preparation of this manuscript.