Objective: To observe the effect of fire needling on prostate symptoms, quality of life, average daily number of nightly urination, urine flow rate and prostat volume in patients with mild to moderate benign prostatic hyperplasia (BPH) of kidney yang deficiency.
Methods: A total of 60 patients with mild to moderate BPH of kidney yang deficiency were randomly divided into an observation group (30 cases, 3 cases dropped off) and a control group (30 cases, 4 cases dropped off). The observation group was treated with fire needling at Guanyuan (CV 4), Shuidao (ST 28) and Qugu (CV 2) twice a week (2-3 d interval between each treatment), continuous treatment for 4 weeks. The control group received lifestyle advice and education, once a week for 4 weeks. In the two groups, the international prostate symptom score (IPSS), the quality of life (QoL) score and the average daily number of nightly urination were observed before treatment, after treatment and during the follow-up of the 4th week; the urinary maximum flow rate (Qmax), the average flow rate (Qave), and the prostate volume were assessed before and after treatment in the two groups. The safety was observed in the observation group.
Results: After treatment and during follow-up, the IPSS scores, QoL scores, and the average daily number of nightly urination in the observation group were decreased compared with those before treatment (P<0.05), and those in the observation group were lower than the control group (P<0.05). After treatment, there was no significant difference in Qmax, Qave and prostate volume between the two groups and within the each group (P>0.05). There were no fire needling-related adverse reactions, and no obvious abnormality was found in urine routine and coagulation function tests before and after treatment in the observation group.
Conclusion: Fire needling can improve lower urinary tract symptoms and quality of life, reduce frequency of nightly urination in patients with mild to moderate BPH of kidney yang deficiency, and has good safety.
目的：观察火针治疗对轻中度肾阳亏虚型良性前列腺增生（BPH）前列腺症状、患者生活质量、平均每日夜尿次数、尿流率、前列腺体积的影响。方法：将60例轻中度肾阳亏虚型BPH患者随机分为观察组（30例，脱落3例）和对照组（30例，脱落4例）。观察组于关元、水道、曲骨行火针治疗，每周治疗2次（间隔2~3 d治疗1次），连续治疗4周。对照组予生活方式指导，每周1次，连续观察4周。分别于治疗前后及随访第4周观察两组患者国际前列腺症状评分（IPSS）、生活质量（QoL）评分、平均每日夜尿次数，于治疗前后观察两组患者最大尿流率（Qmax）、平均尿流率（Qave）及前列腺体积，并记录观察组不良反应情况。结果：治疗后、随访时，观察组患者IPSS评分、QoL评分、平均每日夜尿次数均较治疗前降低（P<0.05），且观察组均低于对照组（P<0.05）。治疗后，两组患者Qmax、Qave、前列腺体积组间及组内比较，差异均无统计学意义（P>0.05）。观察组未出现火针相关不良反应，治疗前后尿常规及凝血功能检查均未见明显异常。结论：火针治疗可改善轻中度肾阳亏虚型BPH患者下尿路症状，提高患者生活质量，减少夜尿次数，具有较好的安全性。.
Keywords: benign prostatic hyperplasia, mild to moderate; fire needling; kidney yang deficiency; randomized controlled trial (RCT).