Farnesane sesquiterpenoids from Rubus delavayi and their anti- Trichinella spiralis activities

Nat Prod Res. 2023 Nov-Dec;37(23):3977-3983. doi: 10.1080/14786419.2023.2164856. Epub 2023 Jan 9.

Abstract

Two new farnesane sesquiterpenoid glycosides, rubusdelosides A and B (1 and 4), together with five known farnesane sesquiterpenoids (2, 3, and 5-7), and two known meroterpenoids (8 and 9), were isolated from water extract of the herbs of R. delavayi. Their structures were identified by the comprehensive analyses of physicochemical properties and spectroscopic data (NMR and HR-ESI-MS). Compounds 1-8 showed moderate in vivo anti-T. spiralis activities.

Keywords: Rosaceae; Rubus delavayi; anti-Trichinella spiralis; farnesane sesquiterpenoids; structural elucidation.

MeSH terms

  • Glycosides
  • Rubus*
  • Sesquiterpenes* / pharmacology
  • Water

Substances

  • Sesquiterpenes
  • Glycosides
  • Water