Predictive Performance of Gram Staining of Catheter Tips for Candida Catheter-Related Bloodstream Infections

Gen Yamada; Noriko Iwamoto; Masahiro Ishikane; Ataru Moriya; Masami Kurokawa; Kazuhisa Mezaki; Norio Ohmagari

doi:10.1093/ofid/ofac667

Predictive Performance of Gram Staining of Catheter Tips for Candida Catheter-Related Bloodstream Infections

Open Forum Infect Dis. 2022 Dec 12;9(12):ofac667. doi: 10.1093/ofid/ofac667. eCollection 2022 Dec.

Authors

Gen Yamada¹, Noriko Iwamoto¹, Masahiro Ishikane¹, Ataru Moriya², Masami Kurokawa², Kazuhisa Mezaki², Norio Ohmagari¹

Affiliations

¹ Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
² Clinical Laboratory Department, National Center for Global Health and Medicine, Tokyo, Japan.

Abstract

We analyzed 2462 episodes of suspected catheter-related bloodstream infection (CRBSI). The sensitivity, specificity, and positive and negative predictive values for detecting Candida CRBSI by gram staining of catheter tips were 66.1%, 99.4%, 84.4%, and 98.4%, respectively. Gram staining may be useful for the early detection of Candida CRBSI.

Keywords: CRBSI; Candida; catheter tips; gram stain; prediction.