Effects of E-Cigarette Flavor Enhancing Capsules on Inhalable Aerosols

Chem Res Toxicol. 2023 Jan 16;36(1):8-13. doi: 10.1021/acs.chemrestox.2c00273. Epub 2022 Dec 9.

Abstract

The flavor of inhaled e-cigarette aerosols may be augmented using crushable flavor capsules added to e-cigarettes. For example, Puff Krush contains breakable flavor capsules in a sorbent material. The capsules are crushed, and then, aerosol passes through the saturated sorbent material before inhalation. Herein, we used NMR and GC-MS to identify the capsule medium chain triglyceride (MCT) solvent and flavorants in selected Puff Krush flavor capsules and then determined which molecules from the capsule transfer into aerosols. MCTs from the Puff Krush were not found in the aerosols, and ∼50% of Puff Krush flavorants transferred into the aerosol upon vaping.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Administration, Inhalation
  • Aerosols
  • Electronic Nicotine Delivery Systems*
  • Tobacco Products*
  • Vaping*

Substances

  • Aerosols