Cross-continental collaboration for understanding postpartum major depression with psychotic features

Mary Kimmel; Harish Thippeswamy; Astrid Kamperman; H N Madhuri; Karen Putnam; Crystal Schiller; Katie Weinel; Hannah Rackers; Janneke Gilden; Veerle Bergink; Samantha Meltzer-Brody; Prabha Chandra

doi:10.3389/fgwh.2022.996501

Cross-continental collaboration for understanding postpartum major depression with psychotic features

Front Glob Womens Health. 2022 Nov 21:3:996501. doi: 10.3389/fgwh.2022.996501. eCollection 2022.

Authors

Affiliations

¹ Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
² Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.
³ Department of Psychiatry, Eramus Medical Center, Rotterdam, Netherlands.
⁴ Department of Psychiatry, San Jose Medical Center, San Jose, CA, United States.

Abstract

Purpose: Assess postpartum depression and psychotic symptoms from three continents.

Methods: Compare numbers of women with depression and psychotic symptoms, mania with or without psychotic features, or transient non-affective psychosis and medication choice.

Results: The prevalence of postpartum depression and psychosis and treatment choice differed at each site.

Conclusions: Best treatment for postpartum depression with psychotic features has not been established yet. Cross-continental collaboration with similar assessments holds promise to develop best practices for these high risk mother-infant dyads.

Keywords: ECT; lithium; major depression with psychotic features; postpartum depression; postpartum psychosis.