1 Emily M. D'Agostino is with the Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, and is also a guest editor of this special issue. Bryan J. Feger is with the Duke Clinical Research Institute, Duke University School of Medicine. Maria F. Pinzon and Rocio Bailey are with Hispanic Services Council, Tampa, FL. Warren A. Kibbe is with the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, and is also a guest editor of this special issue.