Visible-Light-Driven Synthesis of Aryl Xanthates and Aryl Dithiocarbamates via an Electron Donor-Acceptor Complex

Org Lett. 2022 Dec 9;24(48):8895-8900. doi: 10.1021/acs.orglett.2c03736. Epub 2022 Nov 28.

Abstract

Herein, we report a facile, efficient, and practical protocol that enables the preparation of aryl xanthates and aryl dithiocarbamates from functionalized dibenzothiophenium salts via a photoactivated electron donor-acceptor complex. This mild, metal-free method is operationally simple and has a broad substrate scope and potential utility for late-stage functionalization of natural products and pharmaceuticals. Finally, this method also has redefined the substrate scope and reaction pathway for the Leuckart thiophenol reaction.