Genomic Landscape Highlights Molecular Mechanisms Involved in Silicate Solubilization, Stress Tolerance, and Potential Growth-Promoting Activity of Bacterium Enterobacter sp. LR6

Cells. 2022 Nov 15;11(22):3622. doi: 10.3390/cells11223622.

Abstract

Silicon (Si) is gaining widespread attention due to its prophylactic activity to protect plants under stress conditions. Despite Si's abundance in the earth's crust, most soils do not have enough soluble Si for plants to absorb. In the present study, a silicate-solubilizing bacterium, Enterobacter sp. LR6, was isolated from the rhizospheric soil of rice and subsequently characterized through whole-genome sequencing. The size of the LR6 genome is 5.2 Mb with a GC content of 54.9% and 5182 protein-coding genes. In taxogenomic terms, it is similar to E. hormaechei subsp. xiangfangensis based on average nucleotide identity (ANI) and digital DNA-DNA hybridization (dDDH). LR6 genomic data provided insight into potential genes involved in stress response, secondary metabolite production, and growth promotion. The LR6 genome contains two aquaporins, of which the aquaglyceroporin (GlpF) is responsible for the uptake of metalloids including arsenic (As) and antimony (Sb). The yeast survivability assay confirmed the metalloid transport activity of GlpF. As a biofertilizer, LR6 isolate has a great deal of tolerance to high temperatures (45 °C), salinity (7%), and acidic environments (pH 9). Most importantly, the present study provides an understanding of plant-growth-promoting activity of the silicate-solubilizing bacterium, its adaptation to various stresses, and its uptake of different metalloids including As, Ge, and Si.

Keywords: Enterobacter; GlpF; genome sequencing; metalloid transport; plant-growth-promoting bacteria.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA
  • Enterobacter* / genetics
  • Genomics*
  • Plants / genetics
  • Silicates
  • Silicon

Substances

  • Silicates
  • Silicon
  • DNA

Grants and funding

This research was funded by the Department of Biotechnology (DBT), Government of India (GoI), for the Ramalingaswami Fellowship Award to R.D. and H.S. and grants BT/PR32853/AGIII/103/1159/2019 and BT/PR38279/GET/119/351/2020 to R.D., H.S., and T.R.S.; The Science and Engineering Research Board (SERB), India, Department of Science and Technology (DST), Government of India (GoI), for the JC Bose Fellowship to T.R.S. and research grant CRG/2019/006599 awarded to R.D., H.S., and T.R.S.; and the University Grants Commission (UGC) for the Senior Research Fellowship to G.R.