Endovascular management of pulmonary arteriovenous malformations presenting as multiple brain abscesses

BMJ Case Rep. 2022 Nov 22;15(11):e251593. doi: 10.1136/bcr-2022-251593.

Abstract

Pulmonary arteriovenous malformations (PAVMs) are rare vascular lesions characterised by abnormal connections between the pulmonary artery and vein bypassing the pulmonary capillary bed and causing right-to-left shunt. Paradoxical embolism is known to occur in these cases, leading to inoculation of septic focus in the systemic circulation. We report a case of multiple PAVMs who presented clinically with seizures and altered sensorium. On radiological work-up, multiple brain abscesses and large PAVMs were evident. The patient was successfully treated by endovascular embolisation of the PAVMs using a vascular plug and multiple coils. The patient showed complete clinical recovery and resolution of brain abscesses on follow-up.

Keywords: Infection (neurology); Interventional cardiology; Interventional radiology; Neuroimaging; Radiology (diagnostics).

Publication types

  • Case Reports

MeSH terms

  • Arteriovenous Fistula
  • Arteriovenous Malformations* / complications
  • Arteriovenous Malformations* / diagnostic imaging
  • Arteriovenous Malformations* / therapy
  • Brain Abscess* / diagnostic imaging
  • Brain Abscess* / etiology
  • Brain Abscess* / therapy
  • Endovascular Procedures*
  • Humans
  • Pulmonary Artery / abnormalities
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Veins / abnormalities

Supplementary concepts

  • Pulmonary Arteriovenous Fistulas