Primary Antibody Immunodeficiency and the Pregnant Patient

Abstract

An overview of primary antibody immunodeficiency in pregnancy is presented. Indications for immunoglobulin replacement therapy (IGRT), dosing, and safety considerations are highlighted. Uses of immunizations and antimicrobial therapy are also discussed. In general, IGRT, both intravenous and subcutaneous, is considered safe in pregnancy.

Keywords: IVIG; Immunoglobulin replacement therapy (IGRT); Pregnancy; Primary immunodeficiency (PI); SCIG.