Mouse Corneal Transplantation

Peng Chen; Ki Ho Park; Liqiang Zhang; Alexandra R Lucas; Heather L Chandler; Hua Zhu

doi:10.1007/978-1-0716-2835-5_3

Mouse Corneal Transplantation

Methods Mol Biol. 2023:2597:19-24. doi: 10.1007/978-1-0716-2835-5_3.

Authors

Peng Chen¹, Ki Ho Park¹, Liqiang Zhang², Alexandra R Lucas², Heather L Chandler³, Hua Zhu⁴

Affiliations

¹ Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
² Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, Tempe, AZ, USA.
³ College of Optometry, The Ohio State University, Columbus, OH, USA. Chandler.111@osu.edu.
⁴ Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Hua.Zhu@osumc.edu.

PMID: 36374411
DOI: 10.1007/978-1-0716-2835-5_3

Abstract

Corneal transplantation is the most common form of organ transplantation worldwide. Transplant survival depends on various factors, many of which are not fully understood. Due to the existence of many genetically defined strains, mouse models of corneal transplantation are most commonly used. Here, we describe a method for a mouse corneal transplantation.

Keywords: Corneal transplant; Inflammation; Mouse; Vascularized.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Corneal Transplantation* / methods
Disease Models, Animal
Graft Rejection
Graft Survival
Mice