Cardiovascular autonomic modulation during passive heating protocols: a systematic review

Physiol Meas. 2023 Jan 12;44(1). doi: 10.1088/1361-6579/aca0d9.

Abstract

Objective.To conduct a systematic review of the possible effects of passive heating protocols on cardiovascular autonomic control in healthy individuals.Approach.The studies were obtained from MEDLINE (PubMed), LILACS (BVS), EUROPE PMC (PMC), and SCOPUS databases, simultaneously. Studies were considered eligible if they employed passive heating protocols and investigated cardiovascular autonomic control by spontaneous methods, such as heart rate variability (HRV), systolic blood pressure variability (SBPV), and baroreflex sensitivity (BRS), in healthy adults. The revised Cochrane risk-of-bias tool (RoB-2) was used to assess the risk of bias in each study.Main results.Twenty-seven studies were included in the qualitative synthesis. Whole-body heating protocols caused a reduction in cardiac vagal modulation in 14 studies, and two studies reported both increased sympathetic modulation and vagal withdrawal. Contrariwise, local-heating protocols and sauna bathing seem to increase cardiac vagal modulation. A reduction of BRS was reported in most of the studies that used whole-body heating protocols. However, heating effects on BRS remain controversial due to methodological differences among baroreflex analysis and heating protocols.Significance.Whole-body heat stress may increase sympathetic and reduce vagal modulation to the heart in healthy adults. On the other hand, local-heating therapy and sauna bathing seem to increase cardiac vagal modulation, opposing sympathetic modulation. Nonetheless, further studies should investigate acute and chronic effects of thermal therapy on cardiovascular autonomic control.

Keywords: baroreflex; cardiovascular control; heart rate variability; heat therapy; hyperthermia; thermal therapy; thermoregulation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Adult
  • Autonomic Nervous System* / physiology
  • Autonomic Nervous System* / physiopathology
  • Baroreflex / physiology
  • Blood Pressure / physiology
  • Cardiovascular System* / innervation
  • Cardiovascular System* / physiopathology
  • Heart / innervation
  • Heart / physiology
  • Heart Rate / physiology
  • Hot Temperature / adverse effects
  • Humans
  • Hyperthermia, Induced* / adverse effects
  • Hyperthermia, Induced* / methods