Radiovesicolomics-new approach in medical imaging

Ewa Ł Stępień; Carina Rząca; Paweł Moskal

doi:10.3389/fphys.2022.996985

Radiovesicolomics-new approach in medical imaging

Front Physiol. 2022 Oct 10:13:996985. doi: 10.3389/fphys.2022.996985. eCollection 2022.

Authors

Ewa Ł Stępień^{1

2

3}, Carina Rząca^{1

2

3}, Paweł Moskal^{1

2

3}

Affiliations

¹ Faculty of Physics, Astronomy and Applied Computer Science, M. Smoluchowski Institute of Physics, Jagiellonian University, Kraków, Poland.
² Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, Kraków, Poland.
³ Center for Theranostics, Jagiellonian University, Kraków, Poland.

Abstract

This review introduce extracellular vesicles (EVs) to a molecular imaging field. The idea of modern analyses based on the use of omics studies, using high-throughput methods to characterize the molecular content of a single biological system, vesicolomics seems to be the new approach to collect molecular data about EV content, to find novel biomarkers or therapeutic targets. The use of various imaging techniques, including those based on radionuclides as positron emission tomography (PET) or single photon emission computed tomography (SPECT), combining molecular data on EVs, opens up the new space for radiovesicolomics-a new approach to be used in theranostics.

Keywords: PET; extracellular vesicles; medical imaging; positronium imaging; theranostics; total-body PET.

Publication types

Review