In this 3D video we review the case of a pontomesencephalic cavernous malformation in a 27-year-old woman who presented with hemiparesis and diplopia. The cavernous malformation was completely resected through a subtemporal transtentorial approach and an epitrigeminal brainstem entry zone, with a significant improvement in the patient's hemiparesis. The relevant anatomy is reviewed in detail through multiple anatomical brainstem dissection specimens, as well as high-definition fiber tractography images. The rationale for the approach is analyzed relative to other possible options, and a number of technical pearls are provided. The video can be found here: https://youtu.be/8EoIWL7XqAc.
Keywords: brainstem anatomy; cavernous malformation; safe entry zones; subtemporal transtentorial approach; video.
© 2019, Georgios A. Zenonos, Samir Sur, Maximiliano Nuñez, David T. Fernandes-Cabral, and Jacques J. Morcos.