Diabetes in Pregnancy Study Group India (DIPSI) and WHO (1999) diagnostic criteria for GDM: A meta-analysis

Dimple Rawat; Rinchen Zangmo; Sumit Roy Chowdhury; Arun Kumar Yadav; K Aparna Sharma; Neeta Singh; Shivam Pandey

doi:10.1016/j.dsx.2022.102622

Diabetes in Pregnancy Study Group India (DIPSI) and WHO (1999) diagnostic criteria for GDM: A meta-analysis

Diabetes Metab Syndr. 2022 Oct;16(10):102622. doi: 10.1016/j.dsx.2022.102622. Epub 2022 Sep 23.

Authors

Dimple Rawat¹, Rinchen Zangmo², Sumit Roy Chowdhury³, Arun Kumar Yadav⁴, K Aparna Sharma⁵, Neeta Singh⁶, Shivam Pandey⁷

Affiliations

¹ Clinical Epidemiology Unit, All India Institute of Medical Sciences, New Delhi, India. Electronic address: rawat.dimple96@gmail.com.
² Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: rinchhen.zn@gmail.com.
³ Department of Neuroanesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India. Electronic address: sumitroychowdhury94@gmail.com.
⁴ Department of Community Medicine, Armed Forces Medical College, Pune (AFMC), India. Electronic address: arunyadavpsm@gmail.com.
⁵ Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: kaparnasharma@gmail.com.
⁶ Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: drneetasingh@yahoo.com.
⁷ Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India. Electronic address: dr.pandey.shivam@gmail.com.

PMID: 36201914
DOI: 10.1016/j.dsx.2022.102622

Abstract

Background and aims: The diagnosis of Gestational diabetes mellitus (GDM) is challenging and controversial due to the heterogeneity or lack of consensus regarding the screening and diagnostic criteria for GDM.

Methods: A meta-analysis of studies comparing Diabetes in Pregnancy Study Group India (DIPSI) and WHO 1999 for diagnosing GDM was carried out.

Results: A total of 6 comparative studies were included. Pooled analysis showed sensitivity and specificity as 0.79 (95% CI: 0.53 to 0.92) and 0.97 (95% CI: 0.94 to 0.98) respectively.

Conclusion: Based on the results of the meta-analysis, DIPSI showed higher specificity when compared to WHO 1999, hence may be used to rule in disease in probable GDM cases. However, the results should be interpreted more cautiously and carefully since only a few studies were included.

Keywords: DIPSI; GDM; WHO-1999.

Publication types

Meta-Analysis
Review

MeSH terms

Diabetes, Gestational* / diagnosis
Diabetes, Gestational* / epidemiology
Female
Glucose Tolerance Test
Humans
Mass Screening / methods
Pregnancy
Pregnancy in Diabetics*
World Health Organization