Implementation of a neonatal donation protocol in the neonatal intensive care unit: A single-center experience

Pediatr Transplant. 2022 Dec;26(8):e14403. doi: 10.1111/petr.14403. Epub 2022 Sep 27.

Abstract

Background: Lack of specific protocols for neonatal donation contributes to the rarity of neonatal donors. In this study, we evaluate the impact of the implementation of a neonatal donation protocol in our NICU.

Methods: In this single-center study, we conducted a retrospective chart review of neonatal deaths in our NICU from January 2013 to January 2022. The study was divided into two periods: before and after the implementation of a neonatal donation protocol. The referral rates of potential neonatal donors to the OPO in the two periods were compared using the chi-square test. A p value < .05 was considered statistically significant.

Results: Sixty-four infants were reviewed. Seven (10.9%) met the inclusion criteria for potential neonatal donors after DCC. The referral rate of potential neonatal donors increased from 2.5% to 16.7% after the implementation of this protocol (p = .041), and one infant (4.1%) became an effective heart-valve donor.

Conclusion: The implementation of a local neonatal donation protocol could have contributed to increase the referral rate of potential neonatal donors in our NICU. Following the implementation of a local neonatal donation protocol, we were able to perform a heart-valve donation for the first time in our unit.

Keywords: neonatal donation protocol; neonatal end-of-life care; newborn.

MeSH terms

  • Humans
  • Infant
  • Infant, Newborn
  • Intensive Care Units, Neonatal*
  • Referral and Consultation
  • Retrospective Studies
  • Tissue Donors
  • Tissue and Organ Procurement*