Controversy over sentinel lymph node detection in endometrial cancer

Rev Esp Med Nucl Imagen Mol (Engl Ed). 2022 Nov-Dec;41(6):373-379. doi: 10.1016/j.remnie.2022.09.012. Epub 2022 Sep 24.

Abstract

In the last decade, the procedure of sentinel lymph node biopsy has been introduced in low-risk endometrial cancer, being optional in intermediate- and high-risk cancer. However, until the last year, there was no consensus regarding the group of patients to whom to apply it, the best tracer to use or the site of injection. In this paper, we present in a multidisciplinary view the most controversial issues about the sentinel lymph node procedure in endometrial cancer, emphasizing the pros and cons of the different tracers available: radiotracers, hybrid tracers and indocyanine green.

Keywords: Cáncer de endometrio; Endometrial cancer; Ganglio centinela; Hybrid tracer; Indocyanine green; Linfadenectomía; Lymphadenectomy; Radiotracer; Radiotrazador; Sentinel lymph node; Trazador híbrido; Verde de indocianina.

MeSH terms

  • Coloring Agents
  • Endometrial Neoplasms* / diagnostic imaging
  • Endometrial Neoplasms* / pathology
  • Female
  • Humans
  • Lymph Node Excision / methods
  • Sentinel Lymph Node Biopsy / methods
  • Sentinel Lymph Node* / diagnostic imaging
  • Sentinel Lymph Node* / pathology

Substances

  • Coloring Agents