Limits of Cardiovascular Adaptation During an Extreme Ultramarathon: Insights From Serial Multidimensional, Multiparametric CMR

Mohamad Rabbani; Alessandro Satriano; Julio Garcia; Skye Thompson; Jian-Nong Wu; Milada Pejevic; Todd Anderson; Antoine Dufour; Aaron Phillips; James A White

doi:10.1016/j.jaccas.2022.05.028

Limits of Cardiovascular Adaptation During an Extreme Ultramarathon: Insights From Serial Multidimensional, Multiparametric CMR

JACC Case Rep. 2022 Sep 7;4(17):1104-1109. doi: 10.1016/j.jaccas.2022.05.028.

Authors

Mohamad Rabbani¹, Alessandro Satriano¹, Julio Garcia^{1

2}, Skye Thompson¹, Jian-Nong Wu², Milada Pejevic¹, Todd Anderson¹, Antoine Dufour^{1

2

3}, Aaron Phillips^{1

2

3}, James A White^{1

2}

Affiliations

¹ Libin Cardiovascular Institute, Department of Cardiac Sciences, Cummings School of Medicine, University of Calgary, Alberta, Canada.
² Department of Diagnostic Imaging, Cummings School of Medicine, University of Calgary, Alberta, Canada.
³ Department of Physiology and Pharmacology, Cummings School of Medicine, University of Calgary, Alberta, Canada.

Abstract

Extreme endurance athletic challenges provide unique opportunities to study the cardiovascular system's capacity for structural, functional, and hemodynamic adaptation. The authors present a case of a male subject who ran 2,469 km, with serial multiparametric cardiac magnetic resonance imaging used to demonstrate adaptive and maladaptive alterations in cardiac remodeling and myocardial tissue health. (Level of Difficulty: Advanced.).

Keywords: 3D-MDA, 3-dimensional myocardial deformation analysis; 4D-flow; 4D-flow, 4-dimensional flow analysis; CMR, cardiac magnetic resonance; ECV, extracellular volume; EDV, end-diastolic volume; ESV, end-systolic volume; LA, left atrium; LV, left ventricle; RV, right ventricular; cardiac magnetic resonance; strain analysis; tissue mapping.

Publication types

Case Reports