Durable Response to Trametinib in an Infant With ERC1-BRAF Infantile Fibrosarcoma-Like Tumor: A Case Report and Literature Review of BRAF-Altered Infantile Fibrosarcoma-Like Tumors

Affiliations

• ¹ Division of Pediatric Hematology-Oncology, Charles-Bruneau Cancer Centre, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Université de Montreal, Montreal, QC, Canada.
• ² Molecular Diagnostics Laboratory, Charles-Bruneau Cancer Center, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montréal, QC, Canada.
• ³ Research Pathology Facility, Lady Davis Institute, Jewish General Hospital, Montreal, QC, Canada.
• ⁴ Department of Radiology, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montreal, QC, Canada.
• ⁵ Department of Medical Imaging, Centre Hospitalier Universitaire (CHU) de Québec, Québec, QC, Canada.
• ⁶ Clinical Pharmacology Laboratory, OPTILAB and Research Center, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montréal, QC, Canada.
• ⁷ Division of Paediatric Surgery, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montréal, QC, Canada.
• ⁸ Department of Pathology, Centre Hospitalier Universitaire (CHU) de Québec, Québec, QC, Canada.
• ⁹ Department of Pediatrics, Centre Hospitalier Universitaire (CHU) Sainte-Justine Research Center, Montréal, QC, Canada.
• ¹⁰ Department of Pathology and Clinical Laboratory Medicine, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montréal, QC, Canada.
• ¹¹ Department of Pediatrics, Centre Mère-Enfant Soleil du Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Québec, QC, Canada.