This article explains the physiologic basis and fundamentals behind the technology of continuous positive airway pressure, bilevel positive airway pressure, and high flow nasal canula. Additionally, it explores some of the core literature behind their clinical applications. It will also compare HFNC with other noninvasive modalities for respiratory failure alongside clinical titration and weaning algorithms in the emergency department setting.
Keywords: Bilevel positive airway pressure; Continuous positive airway pressure; High flow nasal canula; Hypoxemia; Noninvasive ventilation.
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