Splenic Vessels as a Rescue for Pediatric Kidney Retransplantation in Children With Iliac-caval Agenesis or Thrombosis

Transplantation. 2023 Jan 1;107(1):225-230. doi: 10.1097/TP.0000000000004255. Epub 2022 Dec 8.

Abstract

Background: Unavailability of the iliac-caval system due to thrombosis or aberrant anatomy may preclude kidney transplantation (KT) in small infants, exposing them to the complications of long-term dialysis. A tailored approach may enable KT also in these difficult patients.

Methods: We report the cases of 2 pediatric patients with a history of long-term hemodialysis, a previously failed KT, pending exhaustion of vascular accesses for dialysis, and unsuitability of the iliac-caval axis as a site for KT. Both patients were successfully managed by using splenic vessels as a source of arterial inflow or venous drainage during KT. Notably, one patient also had a previous liver transplant.

Results: Both kidney grafts showed primary function. Posttransplant courses were uneventful, and no rejection episode was observed. At 64- and 10-mo follow-ups, both children had optimal renal function and excellent quality of life.

Conclusions: When the iliac-caval system is unavailable, kidney graft implantation on splenic vessels represents a safe and effective option for pediatric KT.

MeSH terms

  • Child
  • Humans
  • Kidney / physiology
  • Kidney / surgery
  • Kidney Transplantation* / adverse effects
  • Quality of Life
  • Renal Dialysis
  • Reoperation
  • Thrombosis* / etiology
  • Thrombosis* / surgery